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博士研究生
皮肤模型与微流控技术

            投递简历方式:yingping@simplitech.cn

发布时间:2025-10-28 16:52:23   浏览:25

职位描述

[海外留学 皮肤模型 微流控]

我是一个普通文本组件

我是一个普通文本组件

波兰 西里西亚理工大学 生物技术中心 正在招募博士

  1. 学校简介

西里西亚理工大学是该地区最古老的技术大学,也是波兰最负盛名的大学之一。 它成立于1945年,是波兰工业化程度最高的西里西亚科学和教育机构,也是欧洲工业化程度最高的地区之一。

  1. 项目简介

项目名为 "3D 生物打印血管化全厚度皮肤模型作为体外测试的先进平台 ",西里西亚理工大学与格罗宁根大学合作开展双博士学位项目,目的是开发先进的个性化皮肤模型,该模型能够紧密模拟人类皮肤的三层结构:表皮、真皮和皮下脂肪组织。该项目将重点关注尖端生物制造技术与微流体平台的功能整合,包括熔融电泳(MEW)和体积生物打印(VBP)。工程模型将提供一个高度可调、血管化和生物功能性的平台,适用于再生医学、毒理学和转化研究。

  1. 招生详情

学位类型:博士(PhD),获得两个博士学位(西里西亚理工大学和格罗宁根大学)

研究方向:该博士研究员将在设计和制造功能性管状结构方面发挥关键作用,并为三层皮肤构造的血管化模型创建灌注系统,将纤维状 MEW 结构与由各种类型细胞填充的凝胶基质融为一体。

工作包括将皮肤模型与微流控技术相结合,并对这些动态培养系统进行分析。这将包括流体流动的建模和分析、微流体芯片的设计、各种灌注条件下细胞性能的研究以及通过微流体通道进行药物输送的探索。

计划入学时间:2025.12.1

申请截止时间:2025.11.6

薪酬福利:在整个学习期间,奖学金总额为每月 7,000 波兰兹罗提(净额约为 5,970 波兰兹罗提,相当于每月约 1,400 欧元)。在荷兰逗留期间将提供补充资金。

  1. 申请要求

学术背景:

生物医学物理学、材料科学、生物医学工程或相关领域的硕士学位。

微流控技术和组织工程方面拥有丰富的经验,并在简历或出版物中得到明确证明。

其他优势:材料工程、三维打印、显微镜和材料测试方面的专业知识,具有细胞培养经验。

实习或在期刊上发表论文等国际研究经验将受到高度重视。

充满热情、适应能力强、对知识充满好奇心、对研究和科学探索有强烈动力。

语言:熟练掌握英语口语和写作

申请材料:动机信,个人简历,一份文凭复印件,详细联系方式(电子邮件和电话号码),至少两位推荐人的姓名和详细联系方式。

  1. 如何申请&更多信息

申请方式:提交英文申请书至 recruitment@biofabrication.group

详情咨询:dr hab. inż. Malgorzata Wlodarczyk-Biegun, prof. PŚ (Associate Professor): gosia@biofabrication.group

项目官网:https://bip.polsl.pl/oferty_pracy/stypendysta-doktorant-first-team-feng/

信息来源:https://euraxess.ec.europa.eu/jobs/382765

 

Outstanding PhD Candidate needed. Are you willing to take up the challenge?

 

The skin is the largest and one of the most complex organs of the human body, acting as a critical barrier against mechanical injury, infection, dehydration, and harmful environmental factors. While minor wounds can heal spontaneously, extensive skin damage caused by severe burns, trauma, or congenital disorders remains a major therapeutic and clinical challenge. Existing treatments, including wound patches, grafts, commercial skin substitutes, and models, often fall short due to their limited functionality and inability to replicate the complex structure and physiology of native skin closely.

Therefore, in this project, supported by the FNP FIRST TEAM FENG grantno.FENG.02.02-IP.05-0263/24 entitled “3D Bioprinted Vascularized Full-Thickness Skin Models as Advanced Platforms for In Vitro Testing” and conducted as a double doctorate in collaboration with the University of Groningen, we aim to develop advanced, personalised skin models that closely mimic the three-layered architecture of human skin: epidermis, dermis, and subcutaneous adipose tissue. The project will focus on the functional integration of cutting-edge biofabrication technologies, including melt electrowriting (MEW) and volumetric bioprinting (VBP), with microfluidic platforms. The engineered models will provide a highly tunable, vascularised, and biologically functional platform suitable for regenerative medicine, toxicology, and translational research.

Where to apply

E-mail

recruitment@biofabrication.group

Requirements

Research Field

Engineering » Biomedical engineering

Education Level

Master Degree or equivalent

Skills/Qualifications

A Master’s degree in biomedical physics, materials science, biomedical engineering, or a related field is required. Candidates must have proven experience in microfluidics and tissue engineering, clearly demonstrated in their CV or publications. Applicants lacking this experience will not be considered. Additional assets include expertise in materials engineering, 3D printing, microscopy (light, fluorescence, and confocal), and material testing. Experience in cell culture will also be considered an advantage. Proficiency in English, both spoken and written, is required. International research experience, such as internships or publications in peer-reviewed journals, will be highly valued. The selected candidate will be expected to participate in the research project actively, attend doctoral-level coursesat the Doctoral School, and take part in teaching activities at both the Silesian University of Technology (SUT) in Gliwice, Poland, and the University of Groningen in the Netherlands.

Specific Requirements

We are looking for an enthusiastic, adaptable, and intellectually curious doctoral candidate with a strong drive for research and scientific exploration. The ideal applicant will be eager to engage in a dynamic, cross-border doctoral programme, spending significant periods of study and research in both Poland and the Netherlands. We seek an individual who thrives in collaborative, interdisciplinary settings and is comfortable working within a culturally diverse, international research community.

 

The PhD Fellow will play a key role in designing and fabricating functional tubular structures and creating perfusion systems for vascularized models of three-layered skin constructs, integrating fibrous MEW structures with gel-based matrices populated by various cell types. Their work will involve combining skin models with microfluidics and analysing these dynamic culture systems. This will include modelling and analysis of fluid flow, design of microfluidic chips, studies of cell performance under various perfusion conditions, and exploration of drug delivery through microfluidic channels. In addition to experimental contributions, the Fellow will actively participate in project dissemination through presentations at national and international scientific conferences and by publishing research findings in peer-reviewed journals.

Languages

ENGLISH

Level

Excellent

Research Field

Engineering » Biomedical engineering

Years of Research Experience

1 - 4

Additional Information

Benefits

We offer a unique chance to earn two PhD diplomas (from the Silesian University of Technology and the University of Groningen) by participating in an exciting project that addresses relevant societal challenges. The successful candidate will join an attractive, interdisciplinary research environment within a newly established, enthusiastic international team. The project includes a minimum 1.5-year research stay with part of the group in Groningen, followed by continuation in Gliwice. This transnational arrangement is designed to foster international collaboration, enhance scientific impact, and elevate the overall quality of the research conducted. We offer excellent conditions for the development of your independent career and international scientific network. 

 

The PhD Scholarship is offered for a period of four years. The Scholarship amounts to 7,000 gross PLN per month (approximately 5,970 net PLN, equivalent to approximately 1,400 EUR per month) for the entire duration of the studies. The top-up money for the stay in the Netherlands will be provided. 

Eligibility criteria

  1. Submit your application in English by e-mail to: recruitment@biofabrication.group
  2. In the subject, include "PhD Fellow – microfluidics” and your first and last name. 
  3. Your application should contain: a motivation letter describing your research interests and expertise in microfluidic and tissue engineering; a short CV with the description of your key achievements; a copy of your diplomas; your contact details (e-mail and telephone number); names and contact details of at least two potential referees. 
  4. Please include the following statement in your application: “I hereby agree to the processing of my data included in the application documents by Silesian University of Technology, Gliwice, Poland, to carry out the recruitment process.” 

Selection process

Offers that are incomplete or submitted after the deadline will not be considered. The candidates selected for an interview will be contacted after November 6th (please be advised that only candidates selected for an interview will be contacted). The recruitment decision will be based on a combination of scientific merit, motivation, and the applicant’s potential fit within our interdisciplinary and collaborative team culture. The expected date of the final selection is the end of November 2025

For more information about this position and the project, please contact dr hab. inż. Malgorzata Wlodarczyk-Biegun, prof. PŚ (Associate Professor): gosia@biofabrication.group

Additional comments

About the organisation:

This project will be conducted at the Biotechnology Centre of the Silesian University of Technology (SUT) in Gliwice and the University of Groningen. SUT is one of the leading scientific institutions in Poland (ranked within the top 10 Polish research institutions), equipped with cutting-edge infrastructure. The Biotechnology Centre brings together specialists from computer science, environmental science, chemistry, and biology to collaborate on innovative projects in the fields of bioinformatics, medical, environmental, and industrial biotechnology. The research lines include the development of new biomaterials, controlled cellular differentiation, and modelling of bioprocesses.

The Włodarczyk-Biegun lab, established here in 2019, is equipped with several printers, including a multifunctional GeSiM bioprinter with a melt electrowriting printhead, a Felix bioprinter, an FDM printer, an advanced rheometer with DMA function, a goniometer, and its own biological and chemical labs. A state-of-the-art volumetric printer (the second one in Poland) will be purchased from FNP First Team funds to implement the project. The group has solid experience in the field of biofabrication, developing new printable materials, new printing tools for hydrogel-based inks, electrowriting for the reconstruction of hierarchical structures and detailed characterisation of (bio)inks and printed scaffolds (e.g. rheology, SEM, and mechanical research). 

The University of Groningen (RUG) is a highly interdisciplinary and translational science centre, recognised as one of the top research universities in Europe. RUG is a research powerhouse in key domains, including chemistry, biomedicine, materials science, and environmental sciences, with a strong emphasis on both applied and fundamental research. It is equipped with the most modern infrastructure, including advanced facilities for molecular biology, nanotechnology, computational modelling, and clinical research. Research at RUG is characterised by its integrative approach, bringing together specialists from disciplines such as molecular biology, chemistry, physics, artificial intelligence, and medical sciences. Major research lines include the development of molecular machines, biomaterials, systems biology, and personalised medicine, with extensive expertise in bioprocess optimisation and biomedical applications.